PreModificationWarrantsMember
AwardType [Axis]
PostModificationWarrantsMember
ShareBasedCompensationWarrantsOneMember
Range [Axis]
ShareBasedCompensationWarrantsTwoMember
ShareBasedCompensationWarrantsFourMember
ShareBasedCompensationWarrantsFiveMember
ShareBasedCompensationWarrantsSixMember
ShareBasedCompensationWarrantsSevenMember
ShareBasedCompensationWarrantsEightMember
ShareBasedCompensationWarrantsNineMember
ShareBasedCompensationWarrantsTenMember
ShareBasedCompensationWarrantsElevenMember
ShareBasedCompensationWarrantsTwelveMember
February2012ConvertibleNotes12PercentMember
Debt Instrument [Axis]
InvestorRelationServicesMember
StatementEquityComponents [Axis]
InvestorRelationsAndPublicCompanyServicesMember
AdditionalInvestorRelationsServicesMember
WarrantModificationsMember
ForegoingExercisesMember
Platinum [Member]
SeriesAPreferredStockMember
Statement Class Of Stock [Axis]
QualifiedFinancingMember
LegalEntityAxis
LegalEntity [Axis]
Pre-Modification [Member]
Short-term Debt, Type [Axis]
Post-Modification [Member]
CatoBioVentures [Member]
USNationalInstitutesOfHealth [Member]
Collaborative Arrangements and Non-collaborative Arrangements [Axis]
NIHGrantRevenueMember
DeferredRevenueArrangementType [Axis]
Licensing [Member]
NotesPayableToRelatedParties [Member]
Related Party [Axis]
CurrentPortionFour [Member]
MaximumMember
ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsByReportLine [Axis]
MinimumMember
Stock Incentive Plan [Member]
Antidilutive Securities [Axis]
Note 1 [Member]
Note 2 [Member]
Maximum [Member]
Exercise Price Range [Axis]
Minimum [Member]
Fair Value, Inputs, Level 1 [Member]
Fair Value, Hierarchy [Axis]
Fair Value, Inputs, Level 2 [Member]
Fair Value, Inputs, Level 3 [Member]
Senior Note1 [Member]
Senior Note 2 [Member]
Senior Note 3 [Member]
Senior Note 4 [Member]
Senior Note 5 [Member]
Senior NonCurrent [Member]
Seven% Note [Member]
Seven % Current [Member]
Seven % Noncurrent [Member]
M F Note B [Member]
M F Note A [Member]
BurrPilgerMayer [Member]
Desjardins [Member]
McCarthyTetrault [Member]
UniversityHealthNote1 [Member]
Service Provider Notes Total [Member]
Service Providers Current [Member]
Service Providers Noncurrent [Member]
Insurance Company [Member]
Vendor [Member]
Vendor Current [Member]
Vendor Noncurrent [Member]
Unrelated Parties [Member]
Unrelated Parties Current [Member]
Unrelated Parties Noncurrent [Member]
Cato Note 1 [Member]
Cato Note 2 [Member]
Related Parties Aggregate [Member]
Related Parties Current [Member]
Related Parties Noncurrent [Member]
Related Parties After Discount [Member]
Service Providers After Discount [Member]
Senior Note Total [Member]
Senior Note Noncurrent [Member]
Seven % Note [Member]
Seven % Noncurrent [Member]
MF Note A [Member]
Service Providers Total [Member]
MF Note B [Member]
Univ Health Note [Member]
Service Note Current [Member]
Service Notes Noncurrent [Member]
Senior Notes Total [Member]
Service Providers Aggregate [Member]
Related Parties [Member]
Warrant 1 [Member]
Class of Warrant or Right [Axis]
Warrant 2 [Member]
Warrant 3 [Member]
Warrant 4 [Member]
Warrant 5 [Member]
Warrant 6 [Member]
Warrant 7 [Member]
Warrant 8 [Member]
Warrant 9 [Member]
Warrant 10 [Member]
Warrant 11 [Member]
Warrant 12 [Member]
Warrant 13 [Member]
Warrant Modification [Member]
Equity Method Investee, Name [Axis]
Platinum Modifications [Member]
2013 Private Placement [Member]
Note 3 [Member]
Note 4 [Member]
Option [Member]
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs, by Report Line [Axis]
Warrant [Member]
US NIH [Member]
UHN [Member]
Cato [Member]
CBV Note [Member]
CRL Note [Member]
Officer [Member]
Subsequent Event [Member]
Subsequent Event Type [Axis]
Senior Note 6 [Member]
Ten Percent Note [Member]
Autilion AG [Member]
Platinum Mod Series A [Member]
Range High [Member]
Range Low [Member]
Document And Entity Information
Entity Registrant Name
Entity Central Index Key
Document Type
Document Period End Date
Amendment Flag
Current Fiscal Year End Date
Is Entity a Well-known Seasoned Issuer?
Is Entity a Voluntary Filer?
Is Entity's Reporting Status Current?
Entity Filer Category
Entity Public Float
Entity Common Stock, Shares Outstanding
Document Fiscal Period Focus
Document Fiscal Year Focus
Statement of Financial Position [Abstract]
ASSETS
Current assets:
Cash and cash equivalents
Prepaid expenses and other current assets
Total current assets
Property and equipment, net
Security deposits and other assets
Total assets
LIABILITIES AND STOCKHOLDERS' DEFICIT
Current liabilities:
Accounts payable
Accrued expenses
Advance from officer
Current portion of notes payable and accrued interest
Current portion of notes payable and accrued interest to related parties
Convertible promissory notes and accrued interest, net of discount of $200,600 at September 30, 2013
Capital lease obligations
Total current liabilities.
Non-current liabilities:
Senior secured convertible promissory notes, net of discount of $2,170,500 at September 30, 2013 and $1,963,100 at March 31, 2013 and accrued interest
Notes payable, net of discount of $1,004,300 at September 30, 2013 and $1,142,600 at March 31, 2013
Notes payable to related parties, net of discount of $125,900 at September 30, 2013 and $147,200 at March 31, 2013 and accrued interest
Warrant liability
Deferred rent liability
Capital lease obligations
Total non-current liabilities
Total liabilities
Commitments and contingencies
Stockholders' deficit:
Preferred stock, $0.001 par value; 10,000,000 shares, including 500,000 Series A shares, authorized at September 30, 2013 and March 31, 2013; 500,000 Series A shares issued and outstanding at September 30, 2013 and March 31, 2013, respectively
Common stock, $0.001 par value; 200,000,000 shares authorized at September 30, 2013 and March 31, 2013; 24,535,185 and 23,480,169 shares issued at September 30, 2013 and March 31, 2013, respectively
Additional paid-in capital
Treasury stock, at cost, 2,713,308 shares of common stock held at September 30, 2013 and March 31, 2013
Notes receivable from sale of common stock
Deficit accumulated during development stage
Total stockholders' deficit
Total liabilities and stockholders' deficit
Convertible promissory notes and accrued interest, net of discount
Senior secured convertible promissory notes, net of discount
Notes payable, net of discount
Notes payable to related parties, net of discount
Stockholders deficit:
Preferred Stock, par value
Preferred Stock, Authorized
PreferredStockSeriesASharesIssued
PreferredStockSeriesASharesOutstanding
Common Stock, Par Value Par Share
Common Stock, Shares Authorized
Common Stock, Shares, Issued
Treasury Stock, Shares
Income Statement [Abstract]
Revenues:
Grant revenue
Collaboration revenue
Other
Total revenues
Operating expenses:
Research and development
Acquired in-process research and development
General and administrative
Total operating expenses
Loss from operations
Other expenses, net:
Interest expense, net
Change in warrant put and note extension option and warrant liabilities
Loss on early extinguishment of debt
Other income
Loss before income taxes
Income taxes
Net loss
Basic net income (loss) per share
Weighted average shares used in computing basic and diluted net loss per share
Comprehensive loss
Statement of Cash Flows [Abstract]
Cash flows from operating activities:
Net loss
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization
Amortization of imputed discount on non-interest bearing notes
Amortization of discounts on 7%, 7.5% and 10% notes
Amortization of discounts on Platinum notes
Amortization of discounts on August 2010 short-term notes
Amortization of discounts on February 2012 12% convertible notes
Loss (gain) on currency fluctuation
Loss on early extinguishment of debt
Loss on settlements of accounts payable
Change in warrant and put and note term extension option liabilities
Stock-based compensation
Expense related to modification of warrants
Non-cash rent and relocation expense
Fair value of Series C preferred stock, common stock, and warrants granted for services
Fair value of common stock granted for services prior to the Merger
Fair value of common stock granted for services following the Merger
Fair value of warrants granted for services and interest following the Merger
Fair value of additional warrants granted pursuant to exercises of modified warrants (fiscal year 2013) and under Discounted Warrant Exercise Program (fiscal year 2012)
Fair value of common stock issued for note term modification
Interest income on note receivable for stock purchase
Consulting services by related parties settled by issuing promissory notes
Gain on sale of assets
Changes in operating assets and liabilities:
Unbilled contract payments receivable
Prepaid expenses and other current assets
Security deposits and other assets
Accounts payable and accrued expenses
Deferred revenues
Net cash used in operating activities
Cash flows from investing activities:
Purchases of equipment, net
Net cash used in investing activities
Cash flows from financing activities:
Net proceeds from issuance of common stock and warrants, including units
Net proceeds from issuance of preferred stock and warrants
Proceeds from exercise of modified warrants
Proceeds from issuance of notes under line of credit
Proceeds from issuance of 7% note payable to founding stockholder
Proceeds of advance from officer
Net proceeds from issuance of 7% convertible notes
Net proceeds from issuance of 10% convertible notes and warrants
Net proceeds from issuance of Platinum notes and warrants
Net proceeds from issuance of 2008/2010 notes and warrants
Net proceeds from issuance of 2006/2007 notes and warrants
Proceeds from issuance of 7% notes payable
Net proceeds from issuance of August 2010 short-term notes and warrants
Net proceeds from issuance of February 2012 12% convertible notes and warrants
Repayment of capital lease obligations
Repayment of notes
Net cash provided by financing activities
Net increase (decrease) in cash and cash equivalents
Cash and cash equivalents at beginning of period
Cash and cash equivalents at end of period
Notes to Financial Statements
NOTE 1 - History and Organization
NOTE 2 - Basis of Presentation and Going Concern
NOTE 3 - Summary of Significant Accounting Policies
NOTE 4 - Fair Value Measurements
NOTE 5 - Prepaid Expenses
NOTE 6 - Accrued Expenses
NOTE 7 - Convertible Promissory Notes and Other Notes Payable
NOTE 8 - Licensing and Collaborative Agreements
NOTE 9 - Capital Stock
NOTE 10 - Related Party Transactions
NOTE 11 - Subsequent Events
Summary Of Significant Accounting Policies Policies
Basis of Presentation and Going Concern
Use of Estimates
Revenue Recognition
Research and Development Expenses
Stock-Based Compensation
Warrant Liability
Comprehensive Loss
Loss per Common Share
Recent Accounting Pronouncements
Summary Of Significant Accounting Policies Tables
Schedule of antidilutive securities excluded from computation of earnings per share
Fair Value Measurements Tables
Fair value heirarchy for liabilities measured at fair value on a recurring basis
Changes in Level 3 liabilities
Prepaid Expenses Tables
Prepaid Expenses
Accrued Expenses Tables
Accrued Expenses
Convertible Promissory Notes And Other Notes Payable Tables
Convertible Promissory Notes and Other Notes Payable
Components of the discount and interest rates
Capital Stock Tables
Black-Scholes Option Pricing Model
Description of units
Warrant exercises and grants
History And Organization Details Textuals
Outstanding shares acquired
Basis Of Presentation And Going Concern Details Textuals
Accumulated Deficit during its development stage
Cash proceeds from convertible and short-term notes
Cash proceeds from grant awards and other events
Equity issuance
Cash expenditure
Share purchase obligation
Share purchase obligation cash consideration
Initial closing
initial share issuance
Private placement proceeds
Statement [Table]
Statement [Line Items]
Loss per Common Share
Series A preferred stock issued and outstanding
Warrant shares issuable to Platinum upon exercise of common stock warrants by Platinum upon exchange of Series A preferred stock under the terms of the October 11, 2012 Note Purchase and Exchange Agreement
Outstanding options under the 2008 and 1999 Stock Incentive Plans
Outstanding warrants to purchase common stock
Convertible promissory notes and accrued interest
Total
Share-based compensation costs
Granted options to purchase common stock
Exercise price of granted options to purchase common stock
outstanding options
outstanding options, weighted average exercise price
Liabilities, Fair Value Disclosure
Warrant liability
Warrant liability
Recognition of warrant liability during period
Mark to Market gain included in net income
Warrant liability
Prepaid Expenses Details
Prepaid Expenses
Insurance
Rent
Legal fees
Interest receivable on note receivable from sale of common stock
Receivable from landlord
Technology license fees and all other
Total
Accrued Expenses Details
Accrued Expenses
Accrued professional services
Accrued vacation pay and other compensation
Accrued royalties and license fees
All other
Total
Principal Balance
Accrued Interest
Total
Note discount on principal
Note discount on accrued interest
Note discount, total
Face value
Discount attributable to fair value of the warrant
Discount attributable to beneficial conversion feature
Inception date carrying value
Effective Interest Rate
Fair value warrant
Market price per share
Exercise price per share
Risk-free interest rate
Expected term (years)
Volatility
Dividend rate
Change in warrant put and note extension option and warrant liabilities
Interest rate
Gross proceeds
Accrued interest rate per share
Warrants to purchase shares
Investment Warrant exercise price
Deferred Revenue Arrangement Type [Axis]
Legal Entity [Axis]
Monthly research funding payments
Promissory note issuance
Warrant issued with promissory note
Research funding payments
Award upon agreed milestones
Grant revenue
Research and development expenses
Market price per share
Exercise price per share
Risk-free interest rate
Expected term (years)
Volatility
Dividend rate
Fair Value per share
Warrants outstanding
Exercise price per share
Expirate date range
Shares subject to purchase
Purchase obligation
Purchase obligation, per share price
Purchase obligation, aggregate cash consideration
Initial closing of financing
Initial issuance of shares under puchase agreement
Note issued
Note conversion price
Warrant issued
Restricted common stock
Exercise price
Exercise price at grant date
Probability of issuance
Exercised warrants
Cash proceeds from exercise of warrants
Modified warrants exercised
Noncash share compensation paid for professional services
Proceeds from short-term loan
Interest rate on note
Monthly installment payment on debt
Total interest expense
Incurred expenses on research and subsequent other projects
Note issued
Interest rate
Shares issued
Warrant term
Investment Warrant exercise price
Gross proceeds
Additional Investor Relations Services Member.
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
Blackscholes Option Pricing Model Table Text Block.
Custom Element.
Custom element.
Cato Holding Company Member.
Custom Element
Custom Element
Custom Element
Custom Element.
Desjardins Member.
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
February 2012 Convertible Notes 12 Percent Member.
Foregoing Exercises Member.
Investor Relation Services Member.
Investor Relations And Public Company Services Member.
Legal Fees1.
Custom Element
Custom Element
Custom Element.
Custom Element.
Custom element.
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
Custom Element
Notes Payable Discount.
Notes Payable Discount Related Parties.
Custom Element.
Custom Element
Outstanding Shares.
Outstanding Warrants To Purchase Common Stock.
Platinum Member.
Custom element.
Post Modification Warrants Member.
Custom element.
Pre Modification Warrants Member.
Custom Element
Custom Element
Custom Element
Custom Element
Prepaid Expenses TableText Block.
Custom Element
Custom Element
Custom Element
Custom Element
Qualified Financing Member.
Custom Element
Custom Element
Custom Element.
Share Based Compensation Warrants Eight Member.
Share Based Compensation Warrants Eleven Member.
Share Based Compensation Warrants Five Member.
Share Based Compensation Warrants Four Member.
Share Based Compensation Warrants Nine Member.
Share Based Compensation Warrants One Member.
Share Based Compensation Warrants Seven Member.
Share Based Compensation Warrants Six Member.
Share Based Compensation Warrants Ten Member.
Share Based Compensation Warrants Twelve Member.
Share Based Compensation Warrants Two Member.
Total.
Custom element.
Unrelated Parties Member.
Warrant Modifications Member.
SevenPercentNoteCurrentMember
Assets, Current
Assets
Liabilities, Current
Capital Lease Obligations, Noncurrent
Liabilities, Noncurrent
Liabilities
Treasury Stock, Value
Stockholders' Equity Attributable to Parent
Liabilities and Equity
Revenues
Operating Expenses
Operating Income (Loss)
ChangeInPutAndNoteExtensionOptionAndWarrantLiabilities
Income Tax Expense (Benefit)
Net Income (Loss) Attributable to Parent
LossOnEarlyExtinguishmentOfDebt
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Deposit Assets
Net Cash Provided by (Used in) Operating Activities
Payments to Acquire Machinery and Equipment
Net Cash Provided by (Used in) Investing Activities
Net Cash Provided by (Used in) Financing Activities
Cash and Cash Equivalents, Period Increase (Decrease)
Earnings Per Share [Abstract]
Fair Value, Measurement with Unobservable Inputs Reconciliations, Recurring Basis, Liability Value
Prepaid Expense, Current [Abstract]
Prepaid Expense and Other Assets, Current
Accrued Liabilities, Current [Abstract]
Long-term Debt, Gross
Chemicals Revenue
Share-based Compensation Arrangements by Share-based Payment Award, Options, Other Share Increase (Decrease) in Period, Weighted Average Exercise Price
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Period Increase (Decrease), Weighted Average Exercise Price
Fair Value Assumptions, Expected Term
Fair Value Assumptions, Expected Volatility Rate
Fair Value Assumptions, Expected Dividend Rate
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Exercise Price
Investment Warrants, Exercise Price