PreModificationWarrantsMember AwardType [Axis] ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain PostModificationWarrantsMember ShareBasedCompensationWarrantsOneMember Range [Axis] ShareBasedCompensationWarrantsTwoMember ShareBasedCompensationWarrantsThreeMember ShareBasedCompensationWarrantsFourMember ShareBasedCompensationWarrantsFiveMember ShareBasedCompensationWarrantsSixMember ShareBasedCompensationWarrantsSevenMember ShareBasedCompensationWarrantsEightMember ShareBasedCompensationWarrantsNineMember ShareBasedCompensationWarrantsTenMember ShareBasedCompensationWarrantsElevenMember ShareBasedCompensationWarrantsTwelveMember ConvertiblePromissoryNotes12PercentFebruary2012Member DebtInstrument [Axis] Notediscount12PercentConvertiblePromissoryNotesMember Net12PercentConvertiblePromissoryNotesMember RelatedPartiesMember RelatedPartyTransactionsByRelatedParty [Axis] NotePayabletoCatoHoldingCo.7PercentRelatedPartiesMember NoteDiscount7percentRelatedPartiesMember TotalNotesPayableto7PercentRelatedPartiesMember LessCurrentPortion7PercentRelatedPartiesMember NonCurrentPortionAndDiscount7PercentRelatedPartiesMember AccruedOfficersCompensationNotesPayableToOfficersForDefferedSalaryRelatedPartiesMember UnrelatedPartiesMember NotesPayable7PercentAllCurrentUnrelatedPartiesMember NotesPayable7Point5PercentToVendorsBurrAndPilgerAndMayerUnrelatedPartiesMember NotesPayable7Point5PercentToVendorsDesjardinsUnrelatedPartiesMember NotesPayable7Point5PercentToVendorsMcCarthyTetraultUnrelatedPartiesMember NotesPayable7Point5PercentToVendorsMorrisonFoersterUnrelatedPartiesMember NotesPayable7Point5PercentNoteDiscountUnrelatedPartiesMember NotesPayable7Point5PercentTotalNotePayableUnrelatedPartiesMember NotesPayable7Point5PercentLessCurrentPortionUnrelatedPartiesMember NotesPayable7Point5PercentNonCurrentPortionAndDiscountUnrelatedPartiesMember NotesPayable5Point8PercentAnd8PercentToInsurancePremiumFinancingCompanyUnrelatedPartiesMember NotesPayable10PercentToVendorsForaccountsPayableConvertedToNotesPayableUnrelatedPartiesMember NotesPayable10PercentLessCurrentPortionUnrelatedPartiesMember NotesPayable10PercentNonCurrentPortionUrelatedPartiesMember February2012ConvertibleNotes12PercentMember August2010ShortTermNoteConvertedTo7PercentNotePayableMember McCarthyMember MorrisonAndFoersterMember DesjardinsMember InvestorRelationServicesMember StatementEquityComponents [Axis] InvestorRelationsAndPublicCompanyServicesMember AdditionalInvestorRelationsServicesMember WarrantModificationsMember ForegoingExercisesMember PlatinumMember SeriesAPreferredStockMember Statement Class Of Stock [Axis] QualifiedFinancingMember February 2012 12% Convertible Notes Member August 2010 Short-Term Note Converted to 7% Note Payable Member LegalEntityAxis LegalEntity [Axis] LegalEntityAxis LegalEntityAxis LegalEntityAxis LegalEntityAxis SeriesAMember AuctionMarketPreferredSecuritiesStockSeries [Axis] MinimumMember MaximumMember Pre-Modification [Member] Short-term Debt, Type [Axis] Post-Modification [Member] CatoBioVentures [Member] USNationalInstitutesOfHealth [Member] Collaborative Arrangements and Non-collaborative Arrangements [Axis] NIHGrantRevenueMember DeferredRevenueArrangementType [Axis] CatoResearchLtdMember IssuedToPlatinumOnTwoJulyTwoThousandTwelve [Member] Related Party [Axis] IssuedToPlatinumOnThirtyAugustTwoThousandTwelve [Member] SeniorNotesNonCurrent [Member] NoteDiscount [Member] SevenPercentNotesPayableAprilTwoThousandEleven [Member] SevenPercentNotesPayableAugustTwoThousandTwelve [Member] SevenPercentNotesPayable [Member] CurrentPortion [Member] SevenPercentNotesPayableNonCurrentPortion [Member] BurrPilgerMayer [Member] Desjardins [Member] McCarthyTetrault [Member] MayTwoThousandElevenMorrisonFoerster [Member] AugustTwoThousandTwelveMorrisonAndFoersterNoteA [Member] AugustTwoThousandTwelveMorrisonAndFoersterNoteB [Member] NoteDiscountOne [Member] SevenPointFivePercentNotesPayable [Member] CurrentPortionOne [Member] NonCurrentPortionAndDiscount [Member] FivePointEightPercentAndEightPercentNotesPayableToInsurancePremiumFinancingCompanyCurrent [Member] TenPercentNotesPayableToVendorsForAccountsPayableConvertedToNotesPayable [Member] CurrentPortionTwo [Member] NonCurrentPortion [Member] TenPercentNotesPayableToUnrelatedParties [Member] CurrentPortionThree [Member] NonCurrentPortionAndDiscountOne [Member] SevenPercentNotePayableToCatoHolding [Member] NoteDiscountTwo [Member] NotesPayableToRelatedParties [Member] CurrentPortionFour [Member] NonCurrentPortionAndDiscountTwo [Member] FebruaryTwoThousandTwelveTwelvePercentConvertiblePromissoryNotesMember TwelvePercentConvertibleNotesNetNnonCurrent [Member] ShareBasedCompensationWarrantsMember Document And Entity Information Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Current Fiscal Year End Date Is Entity a Well-known Seasoned Issuer? Is Entity a Voluntary Filer? Is Entity's Reporting Status Current? Entity Filer Category Entity Public Float Entity Common Stock, Shares Outstanding Document Fiscal Period Focus Document Fiscal Year Focus Statement of Financial Position [Abstract] ASSETS Current assets: Cash and cash equivalents Unbilled contract payments receivable Prepaid expenses Total current assets Property and equipment, net Security deposits and other assets Total assets LIABILITIES AND STOCKHOLDERS' DEFICIT Current liabilities: Accounts payable Accrued expenses Notes payable and accrued interest Notes payable and accrued interest to related parties Capital lease obligations Deferred revenues Total current liabilities. Non-current liabilities: Senior secured convertible promissory notes and accrued interest Convertible promissory notes, net of discount of $481,300 at September 30, 2012 and $499,300 at March 31, 2012, and accrued interest Notes payable, net of discount of $1,600,400 at September 30, 2012 and $228,900 at March 31, 2012 Notes payable to related parties, net of discount of $18,000 at September 30, 2012 and $24,300 at March 31, 2012 Non-current accounts payable Accrued officers' compensation Capital lease obligations. Total non-current liabilities Total liabilities Commitments and contingencies Stockholders' deficit: Preferred stock, $0.001 par value; 500,000 shares authorized at September 30, 2012 and March 31, 2012; 500,000 and 437,055 Series A shares issued and outstanding at September 30, 2012 and March 31, 2012, respectively Common stock, $0.001 par value; 200,000,000 shares authorized at September 30, 2012 and March 31, 2012; 20,056,558 and 18,704,267 shares issued at September 30, 2012 and March 31, 2012, respectively Additional paid-in capital Treasury stock, at cost, 2,713,308 and 2,083,858 shares of common stock held at September 30, 2012 and March 31, 2012, respectively Notes receivable from sale of common stock Deficit accumulated during development stage Total stockholders' deficit Total liabilities and stockholders' deficit Notes payable, net of discount Notes payable to related parties, net of discount Convertible promissory notes, net of discount Stockholders deficit: Preferred Stock, par value Preferred Stock, Authorized PreferredStockSeriesASharesIssued PreferredStockSeriesASharesOutstanding Common Stock, Par Value Par Share Common Stock, Shares Authorized Common Stock, Shares, Issued Treasury Stock, Shares Income Statement [Abstract] Revenues: Grant revenue Collaboration revenue Other Total revenues Operating expenses: Research and development Acquired in-process research and development General and administrative Total operating expenses Loss from operations Other expenses, net: Interest expense, net Change in put and note extension option and warrant liabilities Loss on early extinguishment of debt Other income Loss before income taxes Income taxes Net loss Basic and diluted net loss per common share Weighted average shares used in computing basic and diluted net loss per common share Comprehensive loss Statement of Cash Flows [Abstract] Cash flows from operating activities: Net loss Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization Amortization of imputed discount on non-interest bearing notes Amortization of discounts on 7%, 7.5% and 10% notes Amortization of discounts on Platinum notes Amortization of discounts on August 2010 short-term notes Amortization of discounts on February 2012 12% convertible notes Loss on early extinguishment of debt Loss on settlements of accounts payable Change in put and note term extension option and warrant liabilities Stock-based compensation Expense related to modification of warrants Fair value of Series C preferred stock, common stock, and warrants granted for services prior to the Merger Fair value of common stock granted for services following the Merger Fair value of warrants granted for services following the Merger Fair value of additional warrants granted pursuant to exercises of modified warrants (May-August 2012) and under Discounted Warrant Exercise Program (2011) Fair value of common stock issued for note term modification Consulting services by related parties settled by issuing promissory notes Gain on sale of assets Changes in operating assets and liabilities: Unbilled contract payments receivable Prepaid expenses and other current assets Security deposits and other assets Accounts payable and accrued expenses Deferred revenues Net cash used in operating activities Cash flows from investing activities: Purchases of equipment, net Net cash used in investing activities Cash flows from financing activities: Net proceeds from issuance of common stock and warrants, including units Net proceeds from issuance of preferred stock and warrants Proceeds from exercise of modified warrants (May-August 2012) and under Discounted Warrant Exercise Program (2011) Proceeds from issuance of notes under line of credit Proceeds from issuance of 7% note payable to founding stockholder Net proceeds from issuance of 7% convertible notes Net proceeds from issuance of 10% convertible notes and warrants Net proceeds from issuance of Platinum notes and warrants Net proceeds from issuance of 2008/2010 notes and warrants Net proceeds from issuance of 2006/2007 notes and warrants Proceeds from issuance of 7% notes payable Net proceeds from issuance of August 2010 short-term notes and warrants Net proceeds from issuance of February 2012 12% convertible notes and warrants Repayment of capital lease obligations Repayment of notes Net cash provided by financing activities Net increase in cash and cash equivalents Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Notes to Financial Statements NOTE 1 - History and Organization NOTE 2 - Basis of Presentation and Going Concern NOTE 3 - Summary of Significant Accounting Policies NOTE 4 - Fair Value Measurements NOTE 5 - Prepaid Expenses NOTE 6 - Accrued Expenses NOTE 7 - Convertible Promissory Notes and Other Notes Payable NOTE 8 - Licensing and Collaborative Agreements NOTE 9 - Capital Stock NOTE 10 - Related Party Transactions NOTE 11 - Subsequent Events Summary Of Significant Accounting Policies Policies Basis of Presentation and Going Concern Use of Estimates Revenue Recognition Research and Development Expenses Stock-Based Compensation Comprehensive Loss Loss per Common Share Recent Accounting Pronouncements Fair Value Measurements Summary Of Significant Accounting Policies Tables Earning Per Share Prepaid Expenses Tables Prepaid Expenses Accrued Expenses Tables Accrued Expenses Convertible Promissory Notes And Other Notes Payable Tables Convertible Promissory Notes and Other Notes Payable Incremental value of the Amended M&F Warrant Capital Stock Tables Black-Scholes Option Pricing Model Warrant exercises and grants History And Organization Details Textuals Awarded by U.S. National Institutes Outstanding shares acquired Share repurchase Shares outstanding at merger Outstanding share representation Number of shares authorized following amendment Number of Preferred shares authorized following amendment Series A Preferred Stock shares Series A Preferred share par value Conversion Rate, Series A Preferred shares Auction Market Preferred Securities, Stock Series [Table] Auction Market Preferred Securities, Stock Series [Line Items] Scenario [Axis] Accumulated Deficit during its development stage July 2012 Plantinum Note principal amount August 2012 Plantinum Note principal amount Cash expenditure maximum Cash expenditure minimum Summary Of Significant Accounting Policies Details Loss per Common Share All series of preferred stock issued and outstanding Outstanding options under the 2008 and 1999 Stock Incentive Plan and 1998 Scientific Advisory Board Plan Outstanding warrants to purchase common stock February 2012 12% convertible promissory notes and accrued interest (1) Total Statement [Table] Statement [Line Items] Share-based compensation costs Granted options to purchase common stock Exercise price of granted options to purchase common stock outstanding options outstanding options, weighted average exercise price Fair Value Measurements Details Textuals convertible promissory notes Original Principle balance of notes Repayment of debt in Percentage Issued warrant to purchase common stock Change in Fair value of the warrant liability increase in the put option and note term extension option liabilities Remaining put option and note term extension option liabilities Aggregated fair value of the warrants Prepaid Expenses Details Prepaid Expenses Investor relations and awareness services paid by issuance of common stock or warrants Insurance Legal fees All other Total Accrued Expenses Details Accrued Expenses Accrued professional services Accrued research and development expenses Accrued vacation pay and other compensation Accrued placement agent fees Accrued registration rights payments All other Total Principal Balance Accrued Interest Total Market price per share Exercise price per share Risk-free interest rate Expected term (years) Volatility Dividend rate Fair Value per share Schedule of Long-term Debt Instruments [Table] Debt Instrument [Line Items] Debt Instrument [Axis] Liability under the Registration Rights Agreement July 2012 Platinum Note August 2012 Platinum Note July and August note Rate Expected gross note proceeds February 2012 Note February Note rate Warrant value Aggregate share value Registration rights agreement liability Legal Entity [Axis] Repayment of note Aggregate principal amount May conversion Exercise price Conversion to long-term note Conversion into 7% note New unsecured promissory note Shares Exercisable Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Award Type [Axis] Assumption: Exercise price per share (weighted average) Exercise price per share Upper Risk-free interest rate Minimum Risk-free interest rate Maximum Expected term (years) Minimum Expected term (years) Maximum Volatility Minimum Volatility Maximum Dividend rate Weighted Average Fair Value per share Warrants option Exercise Price Expiration Date Number of Warrants Equity Components [Axis] Class of Stock [Axis] Purchase of common stock Common stock, exercise price per share Fair value of warrant Market price per share Common stock exercise price per share Contractual term Volatility Expected dividend rate Common stock granted Common stock granted value Common stock granted date market price Cash proceeds from common stock Amounts due for services Common stock purchse discription Increased value of warrants exercised common stock at a weighted average exercise price Preferred stock issued Common stock owned Secured convertible promissory note Convertible promissory note Financing transactions gross proceeds Investment in Qualified Financing Amount of commitments from other investors Period of commitments from other investors Securities stated value per share Authorized and outstanding shares Deferred Revenue Arrangement Type [Axis] Monthly payments Amount paid for UHN royalties Award given to Support development Awarded amount increased to Support development Grant revenue Research and development expenses Business Aquisition Unsecured promissory note issued value Warrants Exercisable Total interest expense on note and the prior line of credit Incurred expenses on research and subsequent other projects BurrPilgerAndMayerLLCMember DesjardinsSecuritiesIncMember McCarthyTetraultLLPMember MorrisonAndFoersterLLPMember Assets, Current Assets Liabilities, Current Liabilities, Noncurrent Liabilities Treasury Stock, Value Stockholders' Equity Attributable to Parent Liabilities and Equity Revenues Operating Expenses Operating Income (Loss) ChangeInPutAndNoteExtensionOptionAndWarrantLiabilities Net Income (Loss) Attributable to Parent LossOnEarlyExtinguishmentOfDebt Increase (Decrease) in Accounts Receivable Increase (Decrease) in Deposit Assets Increase (Decrease) in Deferred Revenue Net Cash Provided by (Used in) Operating Activities Payments to Acquire Machinery and Equipment Net Cash Provided by (Used in) Investing Activities Net Cash Provided by (Used in) Financing Activities Cash and Cash Equivalents, Period Increase (Decrease) Earnings Per Share [Abstract] Prepaid Expense, Current [Abstract] Prepaid Expense and Other Assets, Current Accrued Liabilities, Current [Abstract] Other Accrued Liabilities, Current AggregateInvestmentOwnedAmount Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Fair Value Assumptions, Weighted Average Volatility Rate Chemicals Revenue Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Custom Element Outstanding Options Under 2008 And 1999 Stock Incentive Plan And 1998 Scientific Advisory Board Plan. Outstanding Warrants To Purchase Common Stock. February 2012 12 Convertible Promissory Notes And Accrued Interest1. Total. Investor Relations And Awareness Services Paid By Issuance Of Common Stock Or Warrants. Legal Fees1. Accrued Research And Development Expenses. Accrued Placement Agent Fees. Accrued Registration Rights Payments. Pre Modification Warrants Member. Post Modification Warrants Member. Market Price Per Share. Expected Term Years Maximum. Weighted Average Fair Value Per Share. Share Based Compensation Warrants One Member. Share Based Compensation Warrants Two Member. Share Based Compensation Warrants Three Member. Share Based Compensation Warrants Four Member. Share Based Compensation Warrants Five Member. Share Based Compensation Warrants Six Member. Share Based Compensation Warrants Seven Member. Share Based Compensation Warrants Eight Member. Share Based Compensation Warrants Nine Member. Share Based Compensation Warrants Ten Member. Share Based Compensation Warrants Eleven Member. Share Based Compensation Warrants Twelve Member. Exercise Price. Convertible Promissory Notes 12 Percent February 2012 Member. Note discount 12 Percent Convertible Promissory Notes Member. Net 12 Percent Convertible Promissory Notes Member. Related Parties Member. Note Payable to Cato Holding Co. 7 Percent Related Parties Member. Note Discount 7 percent Related Parties Member. Total Notes Payable to 7 Percent Related Parties Member. Less Current Portion 7 Percent Related Parties Member. Non Current Portion And Discount 7 Percent Related Parties Member. Accrued Officers Compensation Notes Payable To Officers For Deffered Salary Related Parties Member. Unrelated Parties Member. Notes Payable 7 Percent All Current Unrelated Parties Member. Notes Payable 7 Point 5 Percent To Vendors Burr And Pilger And Mayer Unrelated Parties Member. Notes Payable 7 Point 5 Percent To Vendors Desjardins Unrelated Parties Member. Notes Payable 7 Point 5 Percent To Vendors McCarthy Tetrault Unrelated Parties Member. Notes Payable 7 Point 5 Percent To Vendors Morrison Foerster Unrelated Parties Member. Notes Payable 7 Point 5 Percent Note Discount Unrelated Parties Member. Notes Payable 7 Point 5 Percent Total Note Payable Unrelated Parties Member. Notes Payable 7 Point 5 Percent Less Current Portion Unrelated Parties Member. Notes Payable 7 Point 5 Percent Non Current Portion And Discount Unrelated Parties Member. Notes Payable 5 Point 8 Percent And 8 Percent To Insurance Premium Financing Company Unrelated Parties Member. Notes Payable 10 Percent To Vendors For accounts Payable Converted To Notes Payable Unrelated Parties Member. Notes Payable 10 Percent Less Current Portion Unrelated Parties Member. Notes Payable 10 Percent Non Current Portion Urelated Parties Member. Prepaid Expenses TableText Block. Convertible Promissory Notes And Other Notes Payable Table Text Block. Blackscholes Option Pricing Model Table Text Block. Warrant Exercises And Grants Table Text Block. Awarded By U.S. National Institutes. Outstanding Shares. Original Principle Balance Of Notes. Repayment Of Debt In Percentage. Issued Warrant To Purchase Common Stock. Change In Fair Value Of The Warrant Liability. Increase In Put Option And Note Term Extension Option Liabilities. Remaining Put Option And Note Term Extension Option Liabilities. Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Exercise Price. February 2012 Convertible Notes 12 Percent Member. August 2010 Short Term Note Converted To 7 Percent Note Payable Member. McCarthy Member. Morrison And Foerster Member. Desjardins Member. Monthly Payments. Amount Paid For Uhn Royalties. Award Given To Support Development. Awarded Amount Increased To Support Development. Investor Relation Services Member. Investor Relations And Public Company Services Member. Additional Investor Relations Services Member. Warrant Modifications Member. Foregoing Exercises Member. Platinum Member. Qualified Financing Member. Investment Warrants Exercise Price. Share Price1. Share Based Compensation Arrangement By Share Based Payment Award Per Share Weighted Average Price Of Shares Purchased1 Share Based Compensation Arrangement By ShareBased Payment Award Number Of Shares Available For Grant1. Common Stock Value1. Amounts Due For Services. Common Stock Purchse Discription. Increased Value Of Warrants Exercised. Common Stock Owned. Secured Convertible Promissory Note1. Financing Transactions Gross Proceeds. Investment In Qualified Financing. Amount Of Commitments From Other Investors. February 2012 12 Percent Convertible Notes Member. Cato Holding Company Member. Burr Pilger And Mayer LLC Member. Desjardins Securities Inc Member. McCarthy Tetrault LLP Member. Morrison And Foerster LLP Member. Contractual Term1. Period Of Commitments From Other Investors2 Expiration Date. Notes Payable Discount. Notes Payable Discount Related Parties. Convertible Notes Discount. Exercise Price Per Share Weighted Avg. Custom Element Custom Element Custom element. Custom element. Custom element. Custom element. Custom element. Custom element. Custom element. Custom element. Custom element. Custom element. Custom Element. Custom element. Custom element. Custom element. Custom element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom element. Custom element. Custom element.