Equity Components [Axis] Series B Preferred Stock Series C Preferred Stock Series A Preferred Stock Common Stock Additional Paid-in Capital Treasury Stock Accumulated Deficit Income Statement Location [Axis] Research and Development Expense General and Administrative Expense Award Type [Axis] Stock Option Property, Plant and Equipment, Type [Axis] Information Technology Equipment Exercise Price Range [Axis] 0.90 to 1.18 1.19 to 1.46 1.47 to 1.63 1.64 to 15.00 Plan Name [Axis] Amended and Restated 2016 and 2019 Stock Laboratory Equipment Tenant Improvements Antidilutive Securities [Axis] 2016 (formerly 2008) and 2016 Stock Incentive Plans Warrants Warrant One Warrant Two Warrant Three Warrant Four Warrant Five Warrant Six Warrant Seven Warrant Eight Warrant Fall 2019 Private Placement Plan Name [Axis] Additional Warrants Winter 2019 Warrant Modification Pre-Modification Post-Modification December 19, 2019 Warrant Modification Lincoln Park 0.398 to 0.89 Series D Preferred Stock Manufacturing Equipment Minimum Maximum Laboratory, Information Technology and Office Equipment Office furniture and equipment StockIncentive and Ombnibus Equity Incentive Plan Change in Accounting Estimate by Type [Axis] Additions Deductions Cover [Abstract] Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Current Fiscal Year End Date Entity a Well-known Seasoned Issuer Entity a Voluntary Filer Entity's Reporting Status Current Entity Filer Category Entity Emerging Growth Company Entity Small Business Entity Shell Company Entity Interactive Data Current Entity Incorporation, State or Country Code Entity File Number Entity Public Float Entity Common Stock, Shares Outstanding Document Fiscal Period Focus Document Fiscal Year Focus Statement [Table] Statement [Line Items] ASSETS Current assets: Cash and cash equivalents Receivable from collaboration partner Prepaid expenses and other current assets Deferred contract acquisition costs - current portion Total current assets Property and equipment, net Right of use asset - operating lease Deferred offering costs Deferred contract acquisition costs - non-current portion Security deposits and other assets Total assets LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT) Current liabilities: Accounts payable Accrued expenses Current notes payable Deferred revenue - current portion Operating lease obligation - current portion Finance lease obligation - current portion Total current liabilities Non-current liabilities: Accrued dividends on Series B Preferred Stock Deferred revenue - non-current portion Operating lease obligation - non-current portion Finance lease obligation - non-current portion Total non-current liabilities Total liabilities Commitments and contingencies Stockholders' equity (deficit): Preferred stock Common stock, $0.001 par value; 325,000,000 shares and 175,000,000 shares authorized at March 31, 2021 and 2020, respectively; 180,751,234 and 49,348,707 shares issued at March 31, 2021 and 2020, respectively Additional paid-in capital Treasury stock, at cost, 135,665 shares of common stock held at March 31, 2021 and 2020 Accumulated deficit Total stockholders' equity (deficit) Total liabilities and stockholders' equity (deficit) Preferred stock, par value Preferred stock, authorized Preferred stock, issued Preferred stock, outstanding Common stock, par value Common stock, authorized Common stock, issued Treasury stock, shares Income Statement [Abstract] Sublicense revenue Total revenues Operating expenses: Research and development General and administrative Total operating expenses Loss from operations Other expenses, net: Interest income, net Other income Loss before income taxes Income taxes Net loss and comprehensive loss Accrued dividends on Series B Preferred stock Beneficial conversion feature on Series D preferred stock Net loss attributable to common stockholders Basic and diluted net loss attributable to common stockholders per common share Weighted average shares used in computing basic and diluted net loss attributable to common stockholders per common share Statement of Cash Flows [Abstract] Cash flows from operating activities: Net loss Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization Stock-based compensation Expense related to modification of warrants Amortization of fair value of common stock issued for services Amortization of fair value of warrants issued for services Changes in operating assets and liabilities: Receivable from collaboration partner or supplier Prepaid expenses and other current assets Right of use asset - operating lease Operating lease liability Deferred sublicense revenue, net of deferred contract acquisition costs Accounts payable and accrued expenses Net cash used in operating activities Cash flows from investing activities: Purchases of equipment and acquisition of tenant improvements Net cash used in investing activities Cash flows from financing activities: Net proceeds from issuance of common stock and Series D preferred stock Net proceeds from issuance of common stock and warrants, including Units Proceeds from exercise of warrants Proceeds from sale of warrants Net proceeds from sale of common stock under equity line Proceeds from issuance of note under payroll protection plan Repayment of capital lease obligations Repayment of notes payable, including Payroll Protection Plan note Net cash provided by financing activities Net increase in cash and cash equivalents Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Supplemental disclosure of cash flow activities: Cash paid for interest Cash paid for income taxes Supplemental disclosure of noncash activities: Insurance premiums settled by issuing note payable Accrued dividends on Series B Preferred Accrued dividends on Series B Preferred settled upon conversion by issuance of common stock Balances at beginning (in shares) Balances at beginning Stock-based compensation expense Accrued dividends on Series B Preferred stock Proceeds from sale of common stock and warrants for cash in private placement offerings (in shares) Proceeds from sale of common stock and warrants for cash in private placement offerings Proceeds from sale of common stock under equity line, shares Proceeds from sale of common stock under equity line, amount Net proceeds from sale of common stock in public offering, shares Net proceeds from sale of common stock in public offering, amount Net proceeds from sale of common stock and Series D Preferred Stock in public offering, shares Net proceeds from sale of common stock and Series D Preferred Stock in public offering, amount Conversion of Series D Preferred stock to common stock, shares Conversion of Series D Preferred stock to common stock, amount Conversion of Series B Preferred stock to common stock and payment of accrued dividends in common stock, shares Conversion of Series B Preferred stock to common stock and payment of accrued dividends in common stock, amount Sale of common stock pursuant to 2019 Employee Stock Purchase Plan, shares Sale of common stock pursuant to 2019 Employee Stock Purchase Plan, amount Issuance of common stock upon cashless exercise of stock options, shares Issuance of common stock upon cashless exercise of stock options, amount Net proceeds from exercise of stock options for cash, shares Net proceeds from exercise of stock options for cash, amount Issuance of common stock at fair value for professional services, shares Issuance of common stock at fair value for professional services, amount Beneficial conversion feature on Series D Preferred stock Proceeds from sale of warrants in private placement Proceeds from sale of units of common stock and warrants for cash in public offering and concurrent private placement, shares Proceeds from sale of units of common stock and warrants for cash in public offering and concurrent private placement, amount Issuance of commitment shares and net proceeds of initial sale of common stock under equity line, shares Issuance of commitment shares and net proceeds of initial sale of common stock under equity line, amount Proceeds from exercise of warrants (in shares) Increase in fair value attributable to warrant modifications Deemed dividend from beneficial conversion feature of Series D Preferred Stock Balances at end (in shares) Balances at end Organization, Consolidation and Presentation of Financial Statements [Abstract] Description of Business Basis of Presentation and Going Concern Accounting Policies [Abstract] Summary of Significant Accounting Policies Warrant One [Member] Receivable from Collaboration Partner Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract] Prepaid Expenses and Other Current Assets Property, Plant and Equipment [Abstract] Property and Equipment Payables and Accruals [Abstract] Accrued Expenses Debt Disclosure [Abstract] Notes Payable Stockholders' Equity Note [Abstract] Capital Stock Research and Development [Abstract] Research and Development Expenses Income Tax Disclosure [Abstract] Income Taxes Tax effect of warrant modifications Licensing, Sublicensing and Collaborative Agreements Share-based Payment Arrangement [Abstract] Stock Option Plans and 401(k) Plan Related Party Transactions [Abstract] Related Party Transactions Commitments and Contingencies Disclosure [Abstract] Commitments, Contingencies, Guarantees and Indemnifications Subsequent Events [Abstract] Subsequent Events Quarterly Financial Information Disclosure [Abstract] Supplemental Financial Information Use of Estimates Principles of Consolidation Cash and Cash Equivalents Property and Equipment Impairment of Long-Lived Assets Deferred Offering Costs Revenue Recognition Research and Development Expenses Stock-Based Compensation Income Taxes Right of Use Assets and Operating Lease Obligations Concentrations of Credit Risk Fair Value Measurements Warrants Issued in Connection with Equity Financing Comprehensive Loss Loss per Common Share Attributable to Common Stockholders Recent Accounting Pronouncements Schedule of basic and diluted net loss attributable to common stockholders per share Schedule of potentially dilutive securities excluded in determining diluted net loss per common share Schedule of prepaid expenses and other current assets Schedule of property and equipment Depreciation and Amortization Assets subject to financing lease Schedule of accrued expenses Summary of notes payable Carrying value of the debt instruments Schedule of the aggregate allocation unit sales proceeds based on the relative fair values Schedule of Black Scholes option pricing model Schedule of warrant exchanges Additional Warrant Modifications Schedule of outstanding warrants to purchase shares Schedule of reserved shares of common stock for future issuance Schedule of effective income tax rate Schedule of components of the deferred tax assets Unrecognized tax benefits Changes in contract liabilities Schedule of share-based compensation expense Schedule of Black Scholes option valuation model Schedule of stock option plans Modification Black Sholes option valuation model Schedule of stock options outstanding and exercisable Schedule of finance lease obligations Schedule of amortization expense for assets recorded under finance leases Summary of presentation of operating lease Summary of expected lease expense Schedule of future minimum payments under operating leases Other lease disclosure Supplemental disclosure of cash flow information Schedule of quarterly financial information Numerator: Net loss attributable to common stockholders for basic and diluted earnings per share Denominator: Weighted average basic and diluted common shares outstanding Potentially dilutive securities excluded in determining diluted net loss per common share Long-Lived Tangible Asset [Axis] Statistical Measurement [Axis] Estimated useful lives Clinical and nonclinical materials and contract services Insurance All other Property and equipment, gross Accumulated depreciation and amortization Owned assets Leased assets Total depreciation and amortization Office equipment Accumulated depreciation Net book value Accrued for clinical and nonclinical materials, development and contract services Accrued professional services All other Principal Balance : Note payable non-current Accrued Interest : Note payable non-current Total Note payable Market price per share at grant date Exercise price per share Risk-free interest rate Contractual term in years Volatility Dividend rate Number of warrant shares Weighted average fair value per share Exercise price per share Expiration date Warrants outstanding Warrants exercisable Reserved for future issuance Available for future grants Available for future issuance Computed expected tax benefit State income taxes, net of federal benefit Tax effect of warrant modifications Tax effect of research and development credits Tax effect of stock compensation Tax effect of other non-deductible items Expired net operating loss carryforwards Change in valuation allowance (federal only) Income tax expense Deferred tax assets: Net operating loss carryovers Basis differences in fixed assets Research and development credit carryforwards Stock based compensation Operating lease Right of Use asset Accruals and reserves Total deferred tax assets Valuation allowance Net deferred tax assets Unrecognized tax benefit Unrecognized benefit - beginning of period Current period tax position increases Prior period tax position increases Unrecognized benefit - end of period Valuation allowance increase U.S. federal net operating loss carryforwards U.S. federal net operating loss carryforwards subject to expiration U.S. federal net operating loss carryforwards not subject to expiration State net operating loss carryforwards Federal and state research and development tax credit carryforwards Unrecognized benefit - end of period Deferred revenue - current Deferred revenue - noncurrent Deferred revenue Total stock-based compensation expense Exercise price Market price on date of grant Expected term (years) Volatility Expected dividend yield Fair value per share at grant date Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Options outstanding at beginning Options granted Options exercised Options forfeited Options expired Options outstanding at end Options exercisable at end Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Roll Forward] Options outstanding at beginning Options granted Options exercised Options forfeited Options expired Options outstanding at end Options exercisable at end Weighted average grant-date fair value of options granted Number outstanding Weighted average remaining years until expiration Weighted average exercise price Number exercisable Exercisable weighted average exercise price Number of share available for grant under 2019 Plan Aggregate intrinsic value outstanding Unrecognized compensation cost Net book value Fiscal Years Ending March 31, 2022 Future minimum lease payments Less imputed interest included in minimum lease payments Present value of minimum lease payments Less current portion Non-current finance lease obligation Current operating lease obligation Non-current operating lease obligation Total operating lease liability Operating lease cost 2022 2023 2024 2025 2026 Thereafter Total lease expense Less imputed interest Present value of operating lease liabilities Assumed remaining lease term in years Assumed discount rate Cash paid for amounts included in the measurement of lease liabilities Facility rent expense Total operating expenses Loss from operations Interest income (expense), net Loss on extinguishment of accounts payable Loss before income taxes Net loss and comprehensive loss Net loss attributable to common stockholders Carrying value as of the balance sheet date of obligations incurred through that date and payable for development expenses. Refers to amount of accrued dividend on preferred stock during the period. Refers to amount of non current portion of accrued dividend as on balance sheet date. Refers to accrued dividend on series B preferred stock. Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from basis differences in fixed assets. Refer to amount of expense related to modification of warrant exchange during the period. Refers to amount of non cash expense insurance premium settled issuing notes payable during the period. Refers to effective income tax rate reconciliation for warrant modifications. Disclosure regarding of prepaid and other assets. Represents the amount as post reported after the correction of an error or other adjustment. Carrying value of security deposits and other assets as on balance sheet date. Price of a single share of a number of saleable stocks of a company. Information about property i.e. tenant improvements. Security that gives the holder the right to purchase shares of stock in accordance with the terms of the instrument, usually upon payment of a specified amount. Security that gives the holder the right to purchase shares of stock in accordance with the terms of the instrument, usually upon payment of a specified amount. Security that gives the holder the right to purchase shares of stock in accordance with the terms of the instrument, usually upon payment of a specified amount. Security that gives the holder the right to purchase shares of stock in accordance with the terms of the instrument, usually upon payment of a specified amount. Security that gives the holder the right to purchase shares of stock in accordance with the terms of the instrument, usually upon payment of a specified amount. Security that gives the holder the right to purchase shares of stock in accordance with the terms of the instrument, usually upon payment of a specified amount. Assets, Current Assets Liabilities, Current Liabilities, Noncurrent Liabilities Treasury Stock, Value Stockholders' Equity Attributable to Parent Liabilities and Equity Revenues Income Tax Expense (Benefit) AccruedDividendOnSeriesBPreferredStock Increase (Decrease) in Other Receivables Increase (Decrease) in Prepaid Expense and Other Assets Operating Lease, Right-of-Use Asset, Amortization Expense Net Cash Provided by (Used in) Operating Activities Payments to Acquire Property, Plant, and Equipment Net Cash Provided by (Used in) Investing Activities Repayments of Long-term Capital Lease Obligations Repayments of Notes Payable Net Cash Provided by (Used in) Financing Activities Cash and Cash Equivalents, Period Increase (Decrease) Property, Plant and Equipment, Policy [Policy Text Block] Research, Development, and Computer Software, Policy [Policy Text Block] Income Tax, Policy [Policy Text Block] Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Capital Leases, Lessee Balance Sheet, Assets by Major Class, Accumulated Depreciation Other Accrued Liabilities, Current AccruedInterestLongTermNotesPayable Class of Warrant or Right, Exercise Price of Warrants or Rights Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Tax effect of warrant modifications [Default Label] Deferred Tax Assets, Gross Deferred Tax Assets, Valuation Allowance Deferred Tax Assets, Net of Valuation Allowance Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Capital Leases, Future Minimum Payments, Interest Included in Payments Capital Lease Obligations, Current Lessee, Operating Lease, Liability, to be Paid, Year One Lessee, Operating Lease, Liability, Undiscounted Excess Amount