Suicidal Ideation

Suicidal Ideation

According to the WHO, every year approximately 800,000 people worldwide take their own life and many more attempt suicide. Suicidal ideation (SI) is characterized as suicidal thoughts and behavior. The U.S. Centers for Disease Control (CDC) views suicide as a major public health concern in the U.S. as rates of suicide have been increasing for both men and women and across all age groups. Suicide is the 10th leading cause of death in the U.S. and is one of just three leading causes that are on the rise. According to experts in the field of SI, the number of Americans who die by suicide is, since 2010, higher than the number of those who die in motor vehicle accidents. People of all genders, ages, and ethnicities can be at risk for suicide. SI is complex and there is no single cause. The NIMH attributes many different factors to someone making a suicide attempt, including, but not limited to, depression, other mental health disorders or substance abuse. Additionally, according to reports released by the VA, the U.S. Military Veteran population is at significantly higher risk for suicide than the general population.

Suicidal Ideation
PH10-SI-800_000

VistaGen’s Innovation:

We believe PH10 may play a key role in a new treatment paradigm for SI.

Development Status:

Based on results of various IND-enabling preclinical studies, and, after appropriate IND submissions, we will assess potential exploratory Phase 2A development of PH10 for stand-alone treatment of SI and/or adjunctive treatment of SI together with KBT or other oral AD therapies.